WhatDxFree suitability check
WhatDx case guides

Research orientation for health problems that remain unresolved.

These pages organize common diagnostic dead ends into safer observations, record questions and focused clinician questions. They are not diagnosis pages. Use the free suitability check for a case-specific screen.

Check my case — free
Immunology & Derm
Recurrent hives despite normal allergy tests | WhatDxOpen guide →High eosinophils with a persistent skin rash | WhatDxOpen guide →Adult-onset eczema that is not improving with steroid cream | WhatDxOpen guide →Recurrent mouth ulcers with joint pain and normal routine blood tests | WhatDxOpen guide →
Neurology & Nerve
Burning feet or neuropathy symptoms despite normal EMG/MRI | WhatDxOpen guide →Dizziness and a racing heart when standing despite a normal ECG | WhatDxOpen guide →Morning headaches despite a normal brain MRI | WhatDxOpen guide →Internal tremors or muscle twitching despite normal tests | WhatDxOpen guide →
GI & Metabolic
Persistent reflux symptoms despite a normal endoscopy and PPI treatment | WhatDxOpen guide →Chronic diarrhea despite a normal colonoscopy | WhatDxOpen guide →Early fullness, nausea or bloating despite normal endoscopy/ultrasound | WhatDxOpen guide →Persistently elevated liver enzymes despite a normal ultrasound | WhatDxOpen guide →
Rheum & Endocrine
Joint pain or swelling despite normal CRP/ESR and negative ANA | WhatDxOpen guide →Positive ANA with fatigue or joint pain but normal CRP | WhatDxOpen guide →Hypothyroid-like symptoms despite a normal TSH | WhatDxOpen guide →Bone or joint pain with persistently low alkaline phosphatase | WhatDxOpen guide →Recurrent unexplained fevers after negative infection testing | WhatDxOpen guide →
Pediatrics
A child with leg pain during running or hopping | WhatDxOpen guide →A child with recurrent stomach pain despite normal ultrasound/blood tests | WhatDxOpen guide →Recurrent lip/eye swelling with abdominal pain and normal allergy tests | WhatDxOpen guide →