1 minute treatment update

Treatment pearls in your chosen speciality or topic, as they are published, updated every 48 hours.
Last updated on 2022/12/03.





Int J Dermatol 02 Dec. 2022.
Efficacy of the treatment with both H2-antagonist and leukotriene antagonist concurrently in combination with H1-antihistamines for chronic idiopathic urticaria.

Sorry! No treatment pearl could be fetched.

 Pubmed Scholar sci-hub

Rheumatology (Oxford) 02 Dec. 2022.
Beneficial effects of nintedanib on cardiomyopathy in patients with systemic sclerosis: a pilot study.

Our data indicate beneficial signals of nintedanib on cardiomyopathy associated with SSc. The anti-fibrotic effect of nintedanib might not be limited to the lung.

 Pubmed Scholar sci-hub

Oman Med J Nov. 2022.
Why Intralesional Measles-Mumps-Rubella is Superior to Bacillus Calmette-Guérin for Treatment of Warts?

Sorry! No treatment pearl could be fetched.

 Pubmed Scholar sci-hub

JAAD Case Rep Dec. 2022.
Effects of mixed-technology CO and Ga-As laser in patients with hidradenitis suppurativa-A case series.

Sorry! No treatment pearl could be fetched.

 Pubmed Scholar sci-hub

J Parasit Dis Dec. 2022.
Cytotoxic screening and in vitro effect of sodium chlorite against promastigotes.

The results of the present study showed that sodium chlorite could be used as an effective treatment for CL, especially in cases resistant to treatment with pentavalent compounds. However, the toxicity of this substance in high concentrations should be considered in clinical setting

 Pubmed Scholar sci-hub

Postepy Dermatol Alergol Oct. 2022.
Trachyonychia successfully treated with low-dose acitretin in a paediatric patient.

Sorry! No treatment pearl could be fetched.

 Pubmed Scholar sci-hub

Postepy Dermatol Alergol Oct. 2022.
Concentrations of metalloproteinase-1 in patients with morphea treated with phototherapy: a preliminary study.

Our data suggest that there is a possible correlation between MMP-1 concentrations and phototherapy. MMP-1 levels were found to be increased following phototherapy treatment, which may suggest a correlation with better response to treatment in patients with morphea. However, further research is needed.

 Pubmed Scholar sci-hub

Postepy Dermatol Alergol Oct. 2022.
Efficacy of guselkumab compared with adalimumab for psoriasis: a meta-analysis of randomized controlled studies.

Guselkumab showed better efficacy than adalimumab for psoriasis.

 Pubmed Scholar sci-hub

Postepy Dermatol Alergol Oct. 2022.
Analysis of selected genetic variants in psoriasis susceptibility and response to treatment.

Although the genetic variants have an impact on the disease risk, they are unlikely to be useful in personalization of topical therapy.

 Pubmed Scholar sci-hub

Postepy Dermatol Alergol Oct. 2022.
Comparison of the efficacy of novel non-invasive mechanical debridement methods - sterile sponge, monofilament fibre cloth and non-woven cloth impregnated with sodium hyaluronate and phospholipids in relation to traditional sterile gauze.

Results imply that all those methods could be considered as they are well accepted by patients and cause less pain during the procedure, which is essential for good compliance and complete resolution of the lesions.

 Pubmed Scholar sci-hub

Mycoses 01 Dec. 2022.
Correlation of plasma levels of itraconazole with treatment response at 4 weeks in chronic dermatophytosis: Results of a randomized controlled trial.

Cure rates for chronic dermatophytosis were poor with all three itraconazole brands at 4 weeks of treatment. Higher cure rates were obtained with innovator drug as compared to multinational and local generic brands at 4 weeks. Plasma levels of three drugs were however similar, indicating that factors other than serum bioavailability are at play in determining response of chronic dermatophyte infections to oral itraconazole.

 Pubmed Scholar sci-hub

Dermatol Ther (Heidelb) 01 Dec. 2022.
Efficacy and Safety of Dimethyl Fumarate in Patients with Moderate-to-Severe Plaque Psoriasis: Results from a 52-Week Open-Label Phase IV Clinical Trial (DIMESKIN 1).

2017-00136840.

 Pubmed Scholar sci-hub

An Bras Dermatol 28 Nov. 2022.
Analysis of the autoimmune response to BP180 in Chinese stroke patients.

Anti-BP180 antibody values and positive rates were higher in stroke patients than in controls, suggesting that stroke patients may have higher of developing BP.

 Pubmed Scholar sci-hub

J Immunother Cancer Dec. 2022.
Update in the treatment of non-melanoma skin cancers: the use of PD-1 inhibitors in basal cell carcinoma and cutaneous squamous-cell carcinoma.

Adjuvant and neoadjuvant use of cemiplimab and pembrolizumab is also being investigated with several ongoing trials. Further clinical trials of immunotherapy must be prioritized in NMSC for further improvement in outcomes

 Pubmed Scholar sci-hub

Oncotarget 04 Aug. 2022.
Addendum: Immunotherapy in Xeroderma Pigmentosum: a case of advanced cutaneous squamous cell carcinoma treated with cemiplimab and a literature review.

Sorry! No treatment pearl could be fetched.

 Pubmed Scholar sci-hub

Oncotarget 04 Aug. 2022.
Addendum: Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center.

Sorry! No treatment pearl could be fetched.

 Pubmed Scholar sci-hub

JAMA Netw Open 01 Dec. 2022.
Effectiveness of an Intervention to Improve HIV Service Delivery for People Who Inject Drugs in Kazakhstan: A Cluster Trial.

ClinicalTrials.gov Identifier: NCT02796027.

 Pubmed Scholar sci-hub

Arch Dermatol Res 01 Dec. 2022.
Treatment of actinic keratosis: a systematic review.

At present, PDT, cryotherapy, imiquimod, IMB, 5-FU, TCA, AFXL, and combination treatments are similarly efficacious in reducing AKs in immunocompetent patients.Registration: N/A

 Pubmed Scholar sci-hub

Int J Cosmet Sci 01 Dec. 2022.
Jade Material in Vitro and in Vivo: A study on the anti-inflammatory and repair efficacy of jade material on the skin.

The jade materials were able to down-regulate the expression of inflammatory factor genes, up-regulate the expression of growth factor genes, and improve the anti-inflammation and repair ability of skin. Furthermore, the test results of participants with sensitive skin after using the mask containing jade extract showed that the mask has repairing ability.

 Pubmed Scholar sci-hub

J Dermatolog Treat 01 Dec. 2022.
Deucravacitinib in the treatment of psoriasis.

Deucravacitinib has the potential to become a safe, effective, and well-tolerated treatment for patients with moderate-to-severe disease. Future studies will be important to determine the exact role of this drug in the treatment of psoriasis

 Pubmed Scholar sci-hub