1 minute treatment update
Treatment pearls in your chosen speciality or topic, as they are published, updated every 48 hours.
Last updated on 2024/04/25.
Bimekizumab in psoriasis: a monocentric study evaluating short- and mid-term effectiveness and safety profile in a real-world setting.
Our results confirm that this IL17A/F inhibitor is highly effective, with a tolerability profile similar to the one expected from RCTs.
Effectiveness of atopic dermatitis patient education programs - a systematic review and meta-analysis.
Moreover, virtual interventions can be employed as constructive tools for reducing barriers of access to patient education. Future research on educational interventions should utilize various methodologies to encourage individual learning preferences with a focus on adult cohorts
Evaluating the Clinical Utility of Semi-Quantitative Luciferase Immunosorbent Assay Using Antigens in Syphilis Diagnosis and Treatment Monitoring.
Semi-quantitative LISA performs well for syphilis diagnosis while LISA-TP17 is more effective for monitoring syphilis treatment in rabbit models and clinical patients.
Increased susceptibility to ischemia causes exacerbated response to microinjuries in the cirrhotic liver.
Our results demonstrate that the cirrhotic liver has an exacerbated response to microinjuries and increased susceptibility to ischemia from microvascular damage, likely related to the vascular derangements that occur during cirrhosis development. Modifications to the fractional laser tool, such as using a femtosecond laser or reducing the spot size, may be able to prevent large disruptions of perfusion and enable further development of a laser-induced microinjury treatment for cirrhosis
A ranking of treatment efficacy in alopecia areata is not possible without head-to-head studies.
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Secukinumab treatment for inflammatory linear verrucous epidermal nevus.
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Systemic therapy for psoriasis and the risk of cutaneous infections.
In conclusion, our study reveals that systemic therapies may increase the risk of cutaneous viral infections. Therefore, dermatologists should exercise caution in this regard
A case of epidermolysis bullosa pruriginosa with a COL7A1 gene mutation successfully treated with upadacitinib.
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Impact of residual skin lesions and previous biologic treatment failure on patient-reported outcomes in patients with psoriasis receiving biologic treatment.
In conclusion, minimal residual skin lesions and prior biologic treatment failure were associated with poorer patient-reported outcomes in patients with psoriasis. Opting for a biologic agent with the highest predicted efficacy, rather than pursuing a "step-up" approach with a higher possibility of treatment failure, may be a more suitable strategy in the biologic treatment of psoriasis
Efficacy of tofacitinib as an induction agent in severe alopecia areata compared to oral betamethasone weekly pulse.
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Excimer laser for the treatment of incomplete rerepigmentation 1 year after cultured epidermal autograft use for carbon dioxide laser-ablated lesions in patients with stable vitiligo.
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Treatment of severe perinuclear antineutrophil cytoplasmic antibody-associated vasculitis with efgartigimod.
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Inadequate response to antiplatelet therapy in Sneddon's syndrome. Time to re-evaluate management recommendations?
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Successful treatment of rheumatoid neutrophilic panniculitis with tofacitinib.
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Surveillance evaluations in patients with stage I, II, III, or resectable IV melanoma who were treated with curative intent: A systematic review.
Surveillance protocols should be based on individual risk of recurrence and established best practices when formulating follow-up strategies, as suggested by the studies reviewed. Future high-quality studies are needed to clarify the frequency of imaging follow-up strategies, especially in patients with high-risk stage II melanoma.
Response to "Cetrimonium Bromide Patch Test Positivity Is Found With a High Frequency in a Cohort of Patients With Frontal Fibrosing Alopecia".
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Response to "Squamous Cell Carcinoma in Situ Achieves Tumor Clearance in More Mohs Stages Than Invasive Squamous Cell Carcinoma".
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755-nm picosecond laser plus topical 20% azelaic acid compared to topical 20% azelaic acid alone for the treatment of melasma: a randomized, split-face and controlled trial.
The additional use of picosecond laser therapy showed no clinical difference except for subtle differences detected by RCM assessments.The study was registered in the Chinese Clinical Trial Registry (ChiCTR2100051294; 18 September 2021).
Rosacea Core Domain Set for Clinical Trials and Practice: A Consensus Statement.
This core domain set for rosacea research is now available; its adoption by researchers may improve the usefulness of future trials of rosacea therapies by enabling meta-analyses and other comparisons across studies. This core domain set may also be useful in clinical practice.
Successful guselkumab treatment of a refractory psoriasis patient with Graves' disease: a case report.
Finally, switching to guselkumab resulted in the psoriasis lesions significantly improving. These findings suggest that guselkumab might be an effective treatment option for refractory psoriasis combined with GD