1 minute treatment update

Treatment pearls in your chosen speciality or topic, as they are published, updated every 48 hours.
Last updated on 2021/07/29.





Joint Bone Spine 24 Jul. 2021.
Impact of COVID-19 on initiation of biologic therapy prescriptions for chronic inflammatory diseases.

Sorry! No treatment pearl could be fetched.

 Pubmed Scholar sci-hub

J Fam Pract Apr. 2021.
Guarding against nonmelanoma skin cancer in solid organ transplant recipients.

se patients at high risk of skin malignancy.

 Pubmed Scholar sci-hub

Cutis Jun. 2021.
Efficacy of Etanercept in the Treatment of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.

Thirteen patients were treated with a single dose (50 mg) of subcutaneous etanercept. Results of this study support the use of etanercept as a potentially beneficial agent in the treatment of SJS/TEN

 Pubmed Scholar sci-hub

J Dermatol 27 Jul. 2021.
2020 guidelines for the diagnosis and treatment of prurigo.

Expressions for acute, subacute, and chronic forms are not used. These guidelines outline the current concepts and specify treatments for prurigo

 Pubmed Scholar sci-hub

Australas J Dermatol 27 Jul. 2021.
A case of omalizumab as a successful treatment for telangiectasia macularis eruptiva perstans.

Omalizumab shows promise as a potential therapy for mast cell disorders; however, its efficacy in TMEP is yet to be established. This case describes a 72-year-old woman with chronic refractory TMEP achieving symptomatic remission within 4 months of commencing omalizumab therapy

 Pubmed Scholar sci-hub

Australas J Dermatol 27 Jul. 2021.
Successful treatment of idiopathic Harlequin Syndrome with oxybutynin and propranolol.

In this patient, a marked improvement in both hyperhidrosis and facial erythema was noted with this combined therapy. We consider it of interest to highlight the response of our patient to the treatment employed, which may be advantageous in future cases of this rare disorder

 Pubmed Scholar sci-hub

Dermatol Surg 20 Jul. 2021.
Experiences and Perspectives of Patients With Striae: A Survey With Treatment Implications.

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 Pubmed Scholar sci-hub

Dermatol Surg 20 Jul. 2021.
Anetoderma-like Skin Lesions After Vacuum-Assisted Tissue Stabilized-Guided Subcision Treatment of Cellulite.

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 Pubmed Scholar sci-hub

Heliyon 21 Jul. 2021.
Bracing NK cell based therapy to relegate pulmonary inflammation in COVID-19.

In this review, we have outlined the present understanding of the immunological response of NK cells in COVID-19 infection. We have also discussed the possible use of these powerful biological cells as a therapeutic agent in view of preventing immunological harms of SARS-CoV-2 and the current challenges in advocating NK cell therapy for the same

 Pubmed Scholar sci-hub

Sci Rep 26 Jul. 2021.
Role and effectiveness of complex and supervised rehabilitation on overall and hand function in systemic sclerosis patients-one-year follow-up study.

Complex, supervised rehabilitation improves hand and overall function in SSc patients up to 6 months after the treatment but not in the long term. The regular repetition of this rehabilitation program should be recommended every 3-6 months to maintain better hand and overall function

 Pubmed Scholar sci-hub

Am J Hematol 23 Jul. 2021.
Cutaneous T-cell Lymphomas: 2021 update on diagnosis, risk-stratification, and management.

TNMB (tumor, node, metastasis, blood) staging remains the most important prognostic factor in MF/SS and forms the basis for a "risk-adapted," multi-disciplinary approach to treatment. For patients with disease limited to the skin, expectant management or skin-directed therapies is preferred, as both disease-specific and overall survival for these patients is favorable. In contrast, patients with advanced-stage disease with significant nodal, visceral or blood involvement are generally approached with systemic therapies, including biologic-response modifiers, histone deacetylase inhibitors, or antibody-based strategies, in an escalating fashion. In highly-selected patients, allogeneic stem-cell transplantation may be considered, as this may be curative in some patients. This article is protected by copyright. All rights reserved.

 Pubmed Scholar sci-hub

Dermatology 26 Jul. 2021.
Advances in the Etiology, Detection, and Clinical Management of Seborrheic Keratoses.

In light of the discontinuation of ESKATA in late 2019, promising alternatives, such as nitric-zinc and trichloroacetic acid topicals, should be further developed. There is also a need for larger, head-to-head trials of emerging laser therapies to ensure that future treatment standards address diverse patient needs

 Pubmed Scholar sci-hub

J Am Acad Dermatol 23 Jul. 2021.
Comment on: Development of psoriasis during treatment with dupilumab: A systematic review.

Sorry! No treatment pearl could be fetched.

 Pubmed Scholar sci-hub

J Eur Acad Dermatol Venereol 26 Jul. 2021.
New-onset acral lesions on hands after administration of mRNA-1273 vaccine against SARS-CoV-2: Clinical images and histopathological study of 3 cases.

First approved vaccines against SARS-COV-2 (mRNA-1273 and BNT162b2) consists of Messenger Ribonucleic Acid (mRNA), encoding the SARS-CoV-2 spike protein, that penetrate cells and produce spike protein . In these vaccines' clinical trials, chilblain-like lesions were not reported ; however, the World Health Organization warned of the possible of appearance of chilblain-like lesions during SARS-CoV-2 vaccination campaign

 Pubmed Scholar sci-hub

J Eur Acad Dermatol Venereol 26 Jul. 2021.
A Genome-wide association study identified HLA-C associated with the effectiveness of methotrexate for psoriasis treatment.

Methotrexate (MTX), a folic acid reductase inhibitor, is prescribed as the first-line systemic treatment for patients with psoriasis. Although the therapeutic efficacy of MTX has been well demonstrated, patients show substantial heterogeneity in their response to MTX therapies, and the efficacy of MTX in a given patient is unpredictable

 Pubmed Scholar sci-hub

J Eur Acad Dermatol Venereol 26 Jul. 2021.
An integrated safety analysis of treatment-emergent fungal infections in patients with psoriasis treated with ixekizumab from 16 clinical studies.

Biologics that selectively target IL-17 have shown efficacy in the treatment of psoriasis.

 Pubmed Scholar sci-hub

J Eur Acad Dermatol Venereol 26 Jul. 2021.
Scabies is becoming less sensitive to permethrin therapy.

However, their findings did not surprise us. Indeed, since late 2019, following the observation of increasing failures of scabies topical treatments, we have started an observational study on this topic

 Pubmed Scholar sci-hub

J Eur Acad Dermatol Venereol 26 Jul. 2021.
Small vessel vasculitis following Oxford-AstraZeneca vaccination against SARS-CoV-2.

Its high transmission capacity coupled with the lack of effective treatment led to the rapid development of vaccines that today, have been administered in a wide list of countries. As a result, new post-vaccination adverse events continue to be described

 Pubmed Scholar sci-hub

J Eur Acad Dermatol Venereol 26 Jul. 2021.
Treatment-specific evaluation of the modified Glasgow-Prognostic-Score in patients with advanced cutaneous melanoma.

Thus, prognostic and predictive biomarkers including metabolic host factors are needed. The modified Glasgow-prognostic-score (mGPS) is a well-established immuno-nutritional prognostic assessment in various cancers(5-8), but not yet assessed in melanoma

 Pubmed Scholar sci-hub

J Eur Acad Dermatol Venereol 26 Jul. 2021.
Assessing the Responsiveness of Sonographic Biomarkers to Brodalumab Therapy in Hidradenitis Suppurativa.

In Hidradenitis Suppurativa (HS), the identification of disease activity biomarkers is a key priority . Sonographic-based imaging biomarkers have been established as valid measurements of baseline disease activity , however the response of epidermal thickness, tunnel diameter and power Doppler intensity in the setting of pharmacologic therapy is unknown

 Pubmed Scholar sci-hub